達拉帕地產品是Darapladib (SB-480848), is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor (IC?? of 0.25 nM). It produces sustained inhibition of plasma Lp-PLA2?activity in humans receiving intensive atorvastatin therapy.?Lp-PLA2?inhibition with Darapladib also reduces the development of coronary atherosclerotic plaques.