BAR-501產品是BAR-501 is a selective GPBAR1 agonist devoid of any FXR agonistic activity.?It effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1, with an EC???of 1 μM. Exposure of GLUTAg cells to BAR501 (10 μM) increases the expression of GLP-1 mRNA by 2.5 folds.