吡啶產品是Ryuvidine is a potent inhibitor of SET domain-containing protein 8?(SETD8) (IC???= 0.5 μM) that suppresses monomethylation of H4K20?in vitro.?It displays weak inhibiton against cyclin-dependent kinase 4 (Cdk4; IC???= 6 μM for Cdk4/cyclin D1). Induces S phase accumulation in HEK293T cells. Cytotoxic against a range of human cancer cells.