PF-8380產品是PF-8380 is a potent and specific inhibitor of Autotaxin (ATX) (IC?? = 2.8 nM). Modulates lysophosphatidic acid (LPA) levels?in vivo?and?in vitro?by directly inhibiting autotaxin. Autotaxin (ATX) is a secreted enzyme having lysophospholipase D activity.