AZ-960產品是AZ-960 is a potent and specific inhibitor of the?JAK2?kinase with a?Ki?of 0.45 nM. AZ-960 induces growth arrest and apoptosis of human T-cell lymphotropic virus type 1, HTLV-1-infected T cells (MT-1 and MT-2) in parallel with downregulation of the phosphorylated forms of Jak2 and Bcl-2 family proteins including Bcl-2 and Mcl-1.