AT7867產品是AT7867 is a potent inhibitor of Akt isoforms Akt1, 2, and 3 (IC??s = 32, 17, and 47 nM, respectively).?It also inhibits p70S6 kinase and PKA (IC??s = 85 and 20 nM, respectively), but is without effect against a panel of other kinases. AT7867 inhibits growth and induces apoptosis in a variety of cancer cell lines?in vitro?and suppresses tumor growth of PTEN-deficient xenografts in mice.