4μ8攝氏度產品是4μ8C is a selective inhibitor of IRE1α ribonuclease (RNase) activity (IC?? = 60 nM). It blocks substrate access to the active site of IRE1α and inactivates IRE1α-mediated mRNA degradation. Displays no effect on the IRE1α-related endoribonuclease RNase L.