AZ-304產品是AZ-304 is a potent, ATP-competitive dual BRAF kinase inhibitor that inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC??s of 79 nM, 38 nM and 68 nM, respectively. In addition, AZ-304 exhibits significant effect on other kinases such as p38 (IC??, 6 nM), CSF1R (IC??, 35 nM). AZ-304 exerts anti-tumour effects in colorectal cancer independently of BRAF genetic status.