AGK7產品是AGK7 is an inactive control and an isomer of AGK2. AGK2 is a cell-permeable, selective inhibitor of SIRT2 which is a NAD+ (nicotinamide adenine dinucleotide)-dependent deacetylase (IC?? = 3.5 μM). AGK2 rescues α-synuclein toxicity in α-Syn-H4 cells while AGK7 does not affect α-synuclein aggregation. AGK7 inhibits SIRT3 with an IC?? value greater than 5 μM and inhibits SIRT1 and SIRT2 with an IC?? greater than 50 μM.