- 中文名稱
NGFR / p75ECD快速ELISA試劑盒：人（2個板）
- 英文名字
- NGFR/p75ECD Rapid ELISA Kit: Human (2 Plates)
- 供應商
- Biosensis
- 產品貨號
- BEK-2219-2P
- 產品報價
- ￥已停產
- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞
- 背景資料
- The nerve growth factor (NGF) receptor (NGFR), also known as p75 neurotrophin receptor (p75NTR; TNFRS16; CD271) is a common receptor for the neurotrophins NGF, BDNF, NT-3 and NT-4/5. In neurons, p75NTR mediates a variety of physiological functions including survival, apoptosis, neurite outgrowth and synaptic plasticity. A potential pathological role for p75NTR has become evident in recent years. Altered p75NTR expression levels are implicated in degeneration of spinal motor neurons in human and mouse models of amyotrophic lateral sclerosis (ALS). Importantly, the extracellular domain of p75NTR (p75ECD) is shed from the cell membrane and excreted in urine.
- 產品描述
- This ELISA kit consists of a pre-coated mouse monoclonal anti-p75 ECD capture antibody, a biotinylated mouse monoclonal anti-p75 ECD detection antibody and horseradish peroxidase (HRP)-conjugated streptavidin. The addition of a substrate (3,3,5,5-tetramethylbenzidine, TMB) yields a colored reaction product which is directly proportional to the concentration of p75 ECD present in samples and protein standards. A human p75 ECD positive control (QC sample) is provided to assure consistent assay performance.
This NGFR/p75 ECD ELISA kit employs an in-house recombinant human p75 ECD-Fc chimera as standard that has been validated against an externally available p75 ECD-Fc protein. While there is a current lack of a commercially available, true human p75 ECD standard, this ELISA kit allows quantification of human p75 ECD as p75 ECD-Fc human equivalents. Please note that the antibodies used in this ELISA do not cross-react with mouse p75 ECD.
Note: For research use only. Not for diagnostic and clinical purposes.
- 產品特點
- 該ELIAS試劑盒包含：2 x 96孔預包被條孔板（可拆卸）, protein standards, QC sample, detection reagents, heterophilic antibody blocker, wash and sample buffers, substrate buffer and detailed protocols.
- 保存建議
- 廠家推薦冰袋運輸。廠家推薦試劑盒保存于2-8 °C.
- 其他
- Biosensis專注于神經科學領域的抗體和試劑的開發，特別是神經營養因子和神經營養因子受體。 近30年來，Biosensis一直是該領域的全球領航者和OEM供應商。除神經營養因子，我們的神經科學產品組合還被廣泛用于神經退行性疾病、神經發育和神經代謝的研究。重點研究領域包括阿爾茨海默氏癥（AD）、帕金森氏癥（PD）和肌萎縮側索硬化（ALS）疾病，以及自噬和代謝應激障礙，包括肥胖、代謝綜合征的研究、神經免疫學和炎癥。Biosensis的產品系列不僅包括持續增長的神經科學研究抗體系列，還包括200多種定量研究ELISAs試劑盒（1板或2板，自由選擇），組織染色（退化神經元染色試劑盒、病理髓鞘染色試劑盒、淀粉樣斑塊染色試劑等）和細胞可視化試劑（染色）以及針對神經科學和細胞疾病研究的純化的蛋白質。我們的抗體和試劑已被廣泛應用于各種技術，包括蛋白質印跡，免疫組織化學，流式分析，共聚焦顯微鏡實時成像，生物抑制和細胞培養以及克隆。
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- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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