- 中文名稱
重組AITRL，人
- 英文名字
- RecombinantAITRL,Human
- 供應商
- Bioworld
- 產品貨號
- BK0004
- 產品報價
- ￥詢價/10ug
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Activation-Inducible TNF-Related Ligand (AITRL), also known as Glucocorticoid-Induced TNF-Related Ligand (GITRL), belongs to the tumor necrosis factor superfamily (TNFSF). AITRL is a Type II single transmembrane protein and shares low conservation within the extracellular domain with other TNFSF members. AITRL is expressed on macrophages, immature and mature dendritic cells and B cells. Its receptor, Activation-Inducible TNFR family Receptor (AITR), is expressed on T lymphocytes, natural killer (NK) cells, and antigen-presenting cells. Upon binding by AITRL, AITR can be released. AITR activation increases resistance to tumors and viral infections and is involved in autoimmune and inflammatory processes. In addition, activated AITR increases TCR-induced T cell proliferation and cytokine production and rescues T cells and NK cells from apoptosis. Recombinant human Activation-Inducible TNF-Related Ligand (rhAITRL) produced in E.coli is a single non-glycosylated polypeptide chain containing 126 amino acids. A fully biologically active molecule, rhAITRL has a molecular mass of 14.3 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
- 序列
- METAKEPCM AKFGPLPSKW
QMASSEPPCV NKVSDWKLEI
LQNGLYLIYG QVAPNANYND
VAPFEVRLYK NKDMIQTLTN
KSKIQNVGGT YELHVGDTID
LIFNSEHQVL KNNTYWGIIL
LANPQFI
- 來源宿主
- Escherichia coli.
- 溶解建議
- Reconstituted in ddH2O at 100 μg/mL.
- 保存建議
- Lyophilized recombinant human Activation-Inducible TNF-Related Ligand (rhAITRL) remains stable up to 6 months at -80
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業，Bioworld品牌創立以來擁有10000多種常規產品現貨，現有8000多種現貨抗體，以及其他IVD原料，蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢，其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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