- 中文名稱
Actinin-α1 polyclonal antibody
- 英文名字
- Actinin-α1 polyclonal antibody
- 供應商
- Bioworld
- 產品貨號
- BS6194
- 產品報價
- ¥詢價/50ul

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and α-actinins. There are four tissue-specific α-actinins, namely α-actinin-1, α-actinin-2, α-actinin-3 and α-actinin-4, which are localized to muscle and non-muscle cells, including skeletal, cardiac and smooth muscle cells, as well as within the cytoskeleton. Each α-actinin protein contains one Actin-binding domain, two calponin-homology domains, two EF-hand domains and four spectrin repeats, through which they function as bundling proteins that can cross-link F-Actin, thus anchoring Actin to a variety of intracellular structures. Defects in the gene encoding α-actinin-4 are the cause of focal segmental glomerulosclerosis 1 (FSGS1), a common renal lesion characterized by decreasing kidney function and, ultimately, renal failure.
- 應用類型
- WB, IHC
- 免疫原
- Recombinant full length Human Actinin-α1.
- 來源宿主
- Rabbit
- 反應性
- Human, Mouse, Monkey
- 保存建議
- Store at 4
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業,Bioworld品牌創立以來擁有10000多種常規產品現貨,現有8000多種現貨抗體,以及其他IVD原料,蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢,其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

- 注意
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