- 中文名稱
ICAM-2 polyclonal antibody
- 英文名字
- ICAM-2 polyclonal antibody
- 供應商
- Bioworld
- 產品貨號
- BS6630
- 產品報價
- ¥詢價/50ul

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play important, yet separate, roles in embryogenesis and development. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the b2a1 and b2aM Integrins. ICAM-2 functions as a ligand for lymphocyte function-associated antigen-1 (LFA-1) and is involved in leukocyte adhesion. ICAM-3 is highly expressed on the surface of human eosinophils, and when bound to ligand may inhibit eosinophil inflammatory responses and survival. ICAM-4, also known as LW glycoprotein, interacts with Integrins aLb2, aMb2, a4b1, the aV family and aIIbb3, and selective binding to different integrins may be relevant to the pathology in a number of red blood cell associated diseases. Lastly, ICAM-5, expressed on telencephalic neurons, binds CD11a/CD18 and thus may act as an adhesion molecule for leukocyte binding in the central nervous system.
- 應用類型
- WB
- 免疫原
- Recombinant full length Human ICAM-2.
- 來源宿主
- Rabbit
- 反應性
- Human, Mouse
- 保存建議
- Store at 4
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業,Bioworld品牌創立以來擁有10000多種常規產品現貨,現有8000多種現貨抗體,以及其他IVD原料,蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢,其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

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