- 中文名稱
APTX polyclonal antibody
- 英文名字
- APTX polyclonal antibody
- 供應商
- Bioworld
- 產品貨號
- BS7755
- 產品報價
- ¥詢價/50ul

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Aprataxin is a nuclear protein, present in both the nucleoplasm and the nucleolus, which is a member of the histidine triad (HIT) superfamily. Aprataxin is involved in DNA single-strand break repair, mediating protein-protein interactions with molecules responding to DNA damage. Aprataxin contains three conserved domains: an N-terminal forkhead-associated (FHA) domain which mediates protein-protein interactions, a HIT domain that is similar to Hint, and a C-terminal zinc finger domain. Loss of function mutations in APTX, the gene encoding for Aprataxin, destabilize the Aprataxin protein and result in a rare neurological disorder known as ataxia-oculomotor apraxia, characterized by abnormal movements of the head and eyes. These mutations either target the HIT domain or truncate the protein N-terminal to a zinc finger.
- 應用類型
- WB, IF/ICC, IP
- 免疫原
- Recombinant full length Human APTX.
- 來源宿主
- Rabbit
- 反應性
- Human
- 保存建議
- Store at 4
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業,Bioworld品牌創立以來擁有10000多種常規產品現貨,現有8000多種現貨抗體,以及其他IVD原料,蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢,其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

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