- 中文名稱
PROCR polyclonal antibody
- 英文名字
- PROCR polyclonal antibody
- 供應商
- Bioworld
- 產品貨號
- BS7843
- 產品報價
- ¥詢價/50ul

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- Thrombomodulin (TM) is an endothelial specific receptor that forms a complex with Thrombin, a protein with procoagulant, inflammatory and anticoagu-lant effects. The TM/Thrombin complex activates Protein C (PC) to generate activated Protein C (APC) and initiate the APC anticoagulant pathway. APC attenuates Thrombin formation through the inactivation, by limited proteolysis, of two significant cofactors of blood clot formation, Factor Va and Factor VIIIa. This process is augmented by the activity of the endothelial cell Protein C receptor (EPCR), which binds both PC and APC with high affinity. The EPCR gene maps to human chromosome 20q11.2 and encodes an anticoagulant that is preferentially expressed on large blood vessel endothelium in the heart and lung with some expression in capillaries in the lung and skin. EPCR, also designated CCD41 in mouse, is a member of the major histocompatibility complex and displays significant homology to CD1. Soluble plasma EPCR is thought to inhibit the membrane-bound EPCR activation of the APC pathway.
- 應用類型
- WB, IHC
- 免疫原
- Recombinant full length Human PROCR.
- 來源宿主
- Rabbit
- 反應性
- Human, Mouse, Rat
- 保存建議
- Store at 4
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業,Bioworld品牌創立以來擁有10000多種常規產品現貨,現有8000多種現貨抗體,以及其他IVD原料,蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢,其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

- 注意
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