- 中文名稱
ANP32A polyclonal antibody
- 英文名字
- ANP32A polyclonal antibody
- 供應商
- Bioworld
- 產品貨號
- BS7847
- 產品報價
- ¥詢價/50ul

- 產品說明書
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- 購買方式
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- 產品新聞

- 背景資料
- Protein phosphatase 2A PP2A is a major mammalian protein serine/threonine phosphatase that regulates diverse cellular processes. ANP32A, also known as Inhibitor 1 of PP2A (I1PP2A), and inhibitor 2 of PP2A (I2PP2A), which share large sequence similarity, are heat-stable protein inhibitors of the cellular phosphatase activity of PP2A. ANP32A and I2PP2A were initially characterized as putative HLA class II associated proteins Phap I and Phap II. These inhibitor proteins act noncompetitively to selectively inhibit PP2A, but do not affect the phosphatase activity of the related proteins PP1, PP2B and PP2C. The ANP32A protein is localized to both the cytoplasm and the nucleus. In contrast, I2PP2A is located predominantly in the nucleus and is highly expressed in Wilms’ tumor cells. Transient expression of I2PP2A in HEK-293 cells leads to an increase in the DNA binding activity of the proto-oncogene c-Jun.
- 應用類型
- WB, IHC
- 免疫原
- Recombinant full length Human ANP32A.
- 來源宿主
- Rabbit
- 反應性
- Human, Mouse, Rat
- 保存建議
- Store at 4
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業,Bioworld品牌創立以來擁有10000多種常規產品現貨,現有8000多種現貨抗體,以及其他IVD原料,蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢,其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

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