- 中文名稱
MSRA polyclonal antibody
- 英文名字
- MSRA polyclonal antibody
- 供應商
- Bioworld
- 產品貨號
- BS8178
- 產品報價
- ￥詢價/50ul
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Protein-bound methionine residues are among the most susceptible to oxidative stress by biological reactive oxygen species (ROS) such as H2O2, hydroxyl radicals and superoxide ions, which result in the formation of methionine sulfoxide, or Met(O). Methionine sulfoxide reductase (MsrA) is an enzyme that catalyzes the thioredoxin-dependent reduction of Met(O) residues in proteins and in methyl sulfoxide compounds. MsrA is a ubiquitously expressed protein which is found in organisms from yeast to man. Mammalian MsrA is most highly expressed in liver, kidney, macrophages, neutrophils, cerebellum and brain neurons. Oxidation of proteins by ROS is associated with oxidative stress and age-related diseases such as Alzheimer’s disease. Recombinant mammalian MsrA retains enzymatic activity, and overexpression of the protein in yeast and human T cells increases their resistance to oxidative stress. Furthermore, MsrA activity decreases in all regions of the Alzheimer’s disease brain. These findings indicate that MsrA plays an important role in protecting cells against oxidative damage and early cell death.
- 應用類型
- WB, IHC, IF/ICC
- 免疫原
- Recombinant full length Human MSRA.
- 來源宿主
- Rabbit
- 反應性
- Human, Mouse, Rat
- 保存建議
- Store at 4
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業，Bioworld品牌創立以來擁有10000多種常規產品現貨，現有8000多種現貨抗體，以及其他IVD原料，蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢，其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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