- 中文名稱
TNP2 polyclonal antibody
- 英文名字
- TNP2 polyclonal antibody
- 供應商
- Bioworld
- 產品貨號
- BS8428
- 產品報價
- ¥詢價/50ul

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- During mammalian spermiogenesis, histones are transiently replaced by several low molecular weight proteins called transition proteins (TNPs) . Transition proteins facilitate chromatin transformation from the nucleosome structure to the nucleoprotamine structure during spermatid differentiation . Transition protein-2, also known as TNP2, and TP2, maps to human chromosome 16p13.13 and encodes a highly basic nuclear protein. TNP2 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines . TNP2 is not a critical factor for shaping of the sperm nucleus, histone displacement, initiation of chromatin condensation, binding of protamines to DNA, or fertility . However, TNP2 is necessary for maintaining the normal processing of protamine 2 and, consequently, the completion of chromatin condensation. If TNP1 is missing, TNP2 may partially compensate for TNP1, but this dysregulation of nucleoprotein replacement results in an abnormal pattern of chromatin condensation and in reduced fertility .
- 應用類型
- WB
- 免疫原
- Recombinant full length Human TNP2.
- 來源宿主
- Rabbit
- 反應性
- Human
- 保存建議
- Store at 4
- 其他
- Bioworld是專一服務于生命科學研究的專業技術型企業,Bioworld品牌創立以來擁有10000多種常規產品現貨,現有8000多種現貨抗體,以及其他IVD原料,蛋白等現貨產品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優勢,其抗體產品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

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