nd very photostable probe routinely used for imaging of alkyne-containing biomolecules. MB 680R Azide can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free “click chemistry” reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. The brightness and photostability of this dye are best suited to direct imaging of low-abundance targets.nnMB 680R is a bright and photostable near IR dye that emits fluorescence at about 700 nm in the borderline spectral region between far-red and near-IR. MB 680R dye is water soluble and pH-insensitive from pH 4 to pH 10. MB 660R is a rhodamine-based dye, and like rhodamine dyes in general, it is very bright and exceptionally photostable . The superior photostability and excellent brightness of MB 680R makes this dye an ideal for confocal microscopy, single molecule imaging and other applications that demand both brightness and photostability.nnMB 660R dye spectrally is almost identical toCF? 680R Dye and can be used a less expensive alternative to these dyes.nnCF? Dye is a registered trademark of Biotium.
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Click Chemistry Tools(CCT)公司位于美國亞利桑那州斯科茨代爾(Scottsdale,AZ)。自公司成立以來,一致致力于不斷開發和擴展一系列連接產品。他們利用特別新的研究成果研發生產出新穎的交聯和標記試劑。產品被廣泛用于藥物研發、癌癥治療以及各類診斷技術等。此外,CCT還可以提供個性化的定制產品,已滿足不同用戶的需求。目前CCT的產品線主要包括:Azides(Biotin-Azides)試劑、Bis-sulfone交聯試劑、DBCO試劑、TCO試劑、Terminal Alkyne試劑、Tetrazine試劑、標記試劑盒以及分選用底物等。nFluoroprobes公司位于美國亞利桑那州斯科茨代爾(Scottsdale, AZ),自成立以來,一直致力于不斷開發一系列的連接(linker)產品。利用特別新的研究成果研發生產出各類新穎的交聯和標記試劑。其產品被廣泛用于藥物研發與篩選、疾病治療方法和診斷技術等領域。此外,Fluoroprobes還可以根據客戶的個性化需求提供各類定制連接產品。代表產品有Classic Fluorescent Dyes, AZDye, Cyanine Dyes, IR Dyes, MB dyes以及一些標記試劑盒等。nQuanta Biodesign公司位于美國中部的俄亥俄州,成立于1997年。也是專注于生產研發各類標記產品的品牌之一。其研發的產品與dPEG技術相結合,生產出他們獨有的專利產品dPEG Building Blocks and Linkers,被廣泛用于細胞治療和分子診斷等研究領域。另外,還可為廣大科研工作者提供多種化學修飾試劑以及傳統Liner等。n目前上述三個品牌都已被被Vectorlabs收購并整合到Vectorlabs產品中