Ang 1-7 is a biologically active peptide of the renin-angiotensin system. Ang I-7 binds the Mas receptor, which mediates vasodilation and the antiproliferative actions of the heptapeptide. Endogenous Ang 1-7 is generated by angiotensin-converting enzyme 2 (ACE 2) mediated degradation of Ang II. It can also be formed from Ang I or Ang II by other peptidases.
產品描述
Ang 1-7是腎素-血管緊張素系統的一種生物活性肽。 Ang I-7與Mas受體結合,后者介導血管舒張和七肽的抗增殖作用。 血管緊張素轉換酶2(ACE 2)介導的血管緊張素Ⅱ(Ang Ⅱ)降解產生內源性Ang 1-7。 它也可以由Ang I或Ang II通過其它肽酶形成。