Select-HA 900 k是一種透明質酸（HA）制劑，采用重組多殺性巴氏桿菌透明質酸合酶通過體外合成制備，粒徑分布均勻且窄。Select-HA 900 k和Select-HATM是Hyalose LLC的商標。透明質酸（HA）是一種高分子量陰離子多糖（1000 - 10000 kD），由重復二糖組成，是結締組織細胞外基質的幾種糖胺聚糖組分之一。游離HA被肝臟吸收，在肝臟中被降解和回收。數據表明HA水平與局部炎癥和許多疾病的嚴重程度之間的關系，如B或C型肝炎、類風濕性關節炎、肝纖維化等。儲存：-20 °C或以下。建議避免頻繁凍融等分。避免微生物或HA降解酶的污染。出版物1. Jing W. DeAngelis P. L. 單分散透明質酸聚合物的同步化學酶促合成。J Biol Chem 2004 279（40）42345-9.
產品描述
Select-HA 900k is a hyaluronic acid (HA) preparation of uniform and narrow size distribution prepared by in vitro synthesis using recombinant Pasteurella multocida hyaluronan synthase. Select-HA 900k and Select-HAa?￠ is a trademark of Hyalose LLC.Hyaluronic acid (HA) is a high molecular weight anionic polysaccharide (1 000-10 000 kD) composed of repeating disaccharides and is one of several glycosaminoglycan components of the extracellular matrix of connective tissue. Free HA is taken up by the liver where it is degraded and recycled. Data indicates a relationship between HA levels local inflammation and severity of many disease such as hepatitis B or C rheumatoid arthritis liver fibrosis etc.Storage: -20 ?°C or below. Avoid frequent freeze-thaw aliquoting is recommended. Avoid contamination with microbes or HA-degrading enzymes.Publications1. Jing W.; DeAngelis P. L. Synchronized chemoenzymatic synthesis of monodisperse hyaluronan polymers. J Biol Chem 2004 279 (40) 42345-9.
