類異戊二烯化合物是一組不同的天然產物，是所有細胞的必需成分。類異戊二烯由簡單的前體異戊烯基二磷酸（IPP）和二甲基烯丙基二磷酸（DMAPP）生物合成。真核真菌和一些革蘭氏陽性細菌通過甲羥戊酸（MVA）途徑產生IPP，而革蘭氏陰性和一些革蘭氏陽性細菌利用非甲羥戊酸或2-C-甲基-D-β-4-磷酸（MEP）途徑。2 Z 6 E-法呢基二磷酸是由（2 Z 6 E）-法呢基二磷酸合酶催化IPP與香葉基二磷酸（GPP）縮合而成。Z-FPP是在分枝桿菌細胞壁的生物合成中具有核心作用的癸烯基二磷酸的前體。
產品描述
Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes fungi and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. 2Z 6E-farnesyl diphosphate is formed by (2Z 6E)-farnesyl diphosphate synthase catalyzed condensation of IPP with geranyl diphosphate (GPP). Z-FPP is the precursor of decaprenyl diphosphate which has a central role in the biosynthesis of the mycobacterial cell wall.
