B7-H6 is a glycosylated member of the B7 family of immune costimulatory proteins. Orthologs in mouse and rat have not been identified. The Ig-like V domain mediates 1:1 stoichiometric binding of B7-H6 to NKp30 expressed on NK cells. It does not show binding to NKp44, NKp46, or NKG2D. Ligation of NKp30 by B7-H6 induces NK cell activation and target cell cytolysis. B7-H6 is expressed on a wide range of hematopoietic, carcinoma, and melanoma tumor cells, which is consistent with the detection of NKp30 binding sites on many tumors. The expression of NKp30 ligands on tumor cells correlates with tumor cell sensitivity to NKp30-dependent cell lysis.
序列
提供的Human CellExp?B7-H6，人類重組Human CellExp? B7-H6, human recombinant是Biovision品牌中國區域總代理艾美捷科技產品，具體的蛋白序列可查看提供的英文版本產品說明書。
來源宿主
提供的Human CellExp?B7-H6，人類重組Human CellExp? B7-H6, human recombinant產品來源宿主，查看該產品說明書，或者在線咨詢我們。
溶解建議
Reconstitute in 1X PBS to the desired protein concentration.
