BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
序列
提供的Human CellExp?BAFFR / TNFRSF13C,Fc標簽人類重組Human CellExp? BAFFR / TNFRSF13C, Fc Tag Human Recombinant是Biovision品牌中國區域總代理艾美捷科技產品,具體的蛋白序列可查看提供的英文版本產品說明書。
來源宿主
提供的Human CellExp?BAFFR / TNFRSF13C,Fc標簽人類重組Human CellExp? BAFFR / TNFRSF13C, Fc Tag Human Recombinant產品來源宿主,查看該產品說明書,或者在線咨詢我們。
溶解建議
Reconstitute in sterile deionized water to a concentration up to 0.2 mg/ml.