Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of na?ve T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress na?ve T cell proliferation.
序列
提供的Human CellExp?LRRC32 / GARP，Fc標簽，人類重組Human CellExp? LRRC32 / GARP, Fc Tag, Human Recombinant是Biovision品牌中國區域總代理艾美捷科技產品，具體的蛋白序列可查看提供的英文版本產品說明書。
來源宿主
提供的Human CellExp?LRRC32 / GARP，Fc標簽，人類重組Human CellExp? LRRC32 / GARP, Fc Tag, Human Recombinant產品來源宿主，查看該產品說明書，或者在線咨詢我們。
溶解建議
Reconstitute in sterile deionized water to the desired protein concentration.
