NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member β (LIFR-β) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM. Human Recombinant NNT-1/BCSF-3 is a 22.4 kDa protein containing 199 amino acid residues.
序列
提供的NNT-1 / BCSF-3,人類重組NNT-1/BCSF-3, Human Recombinant是Biovision品牌中國區域總代理艾美捷科技產品,具體的蛋白序列可查看提供的英文版本產品說明書。
來源宿主
提供的NNT-1 / BCSF-3,人類重組NNT-1/BCSF-3, Human Recombinant產品來源宿主,查看該產品說明書,或者在線咨詢我們。
溶解建議
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.