YWHAH belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 ETA is found in plants and mammals， and there is 99% identity to the mouse， rat and bovine orthologs. YWHAH gene contains a 7 base pair repeat sequence in its 5’ UTR， and changes in the number of this repeat has been associated with early-onset schizophrenia.
14-3-3 eta is specific to the site of joint inflammation.
14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease， though there is no specific staining for the 14-3-3 eta subunit.
There are 3 different isoforms types of 14-3-3: Beta， Gamma and ETA that are DAL-1/Protein 4.1B-binding proteins.
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來源宿主
大腸桿菌中重組表達
溶解建議
提供的人Tyr-3/Trp-5單氧酶激活蛋白ETA（YWHAH）產品為過濾滅菌的無色溶液；其中人Tyr-3/Trp-5單氧酶激活蛋白ETA（YWHAH）產品溶解于20mM Tris pH 8溶液中.
