BDH2 一抗-BDH2 Primary antibody代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: DHRS6 (dehydrogenase/reductase SDR family member 6), also known as EFA6R, SDR15C1, UCPA-OR,UNQ6308 or BDH2, is a 245 amino acid cytoplasmic protein belonging to the short-chain dehydrogenases/reductases (SDR) family, an evolutionarily conserved family of oxidoreductases found in all forms of life. DHRS6 is a novel, cytosolic type II R-β-hydroxybutyrate dehydrogenase that exists as two alternatively spliced isoforms and may have an essential role as a nutrient or building block in cellular survival. Human DHRS6 and its vertebrate orthologs show high levels of sequence identities to bacterial hydroxybutyrate dehydrogenases. DHRS6 may play an important role in the peripheral utilization of 3-hydroxybutyrate and its cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of DHRS6 make it suitable to convert high levels of circulating 3-hydroxybutyrate into acetoacetate.

其他: ProMab 生物技術公司通過整合生物信息學、分子生物學、蛋白質表達、純化技術、基因克隆、微生物學和免疫學，利用新型高通量技術開發重組蛋白、抗體和工程細胞系并將其商業化。專注于免疫治療領域，特別是 CAR-T/NK 細胞技術。ProMab 還開發了一種新型的 mRNA 脂質納米顆粒（mRNA-LNP）平臺，用于即用型試劑和定制研究服務，以推進現有產品并擴展到更多的研究領域。