UMOD 抗體-UMOD Antibody代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: This gene encodes uromodulin, the most abundant protein innnormal urine. Its excretion in urine follows proteolytic cleavagenof the ectodomain of its glycosyl phosphatidylinosital-anchoredncounterpart that is situated on the luminal cell surface of thenloop of Henle. Uromodulin may act as a constitutive inhibitor ofncalcium crystallization in renal fluids. Excretion of uromodulin innurine may provide defense against urinary tract infections causednby uropathogenic bacteria. Defects in this gene are associated withnthe autosomal dominant renal disorders medullary cystic kidneyndisease-2 (MCKD2) and familial juvenile hyperuricemic nephropathyn(FJHN). These disorders are characterized by juvenile onset ofnhyperuricemia, gout, and progressive renal failure. While severalntranscript variants may exist for this gene, the full-lengthnnatures of only two have been described to date. These twonrepresent the major variants of this gene and encode the samenisoform.

免疫原: This UMOD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-380 amino acids from the Central region of human UMOD.

保存建議: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

其他: ProSci Incorporated于1998年成立于美國加州圣地亞哥市,從事抗體等科研試劑的研發、生產和銷售。產品涵蓋了細胞凋亡、信號轉導、免疫、腫瘤、細胞生物、神經生物、傳染病等領域。ProSci擁有超過30000種單克隆抗體和多克隆抗體。ProSci的抗體大都經免疫親和層析純化,具有高純度、高親和力、特異性強等特點,所有的ProSci抗體都經過了嚴格的驗證測試和質量控制,已保證高質量的產品。此外,ProSci還提供標記二抗,重組蛋白,細胞和組織裂解液,細胞涂片,組織切片,多肽等產品與抗體配套使用。