- 中文名稱
USP7 抗體
- 英文名字
- USP7 Antibody
- 供應商
- ProSci
- 產品貨號
- PSI-58-667
- 產品報價
- ￥詢價/400ul
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Hydrolase that deubiquitinates target proteins such as FOXO4, TP53, MDM2, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and proteasomal degradation. Deubiquitinates TP53 and MDM2 and strongly stabilizes TP53 even in the presence of excess MDM2, and also induces TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Contributes to the overall stabilization and trans-activation capability of the herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 during HSV-1 infection.
- 應用類型
- WB
- 免疫原
- This USP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-348 amino acids from the Central region of human USP7.
- 來源宿主
- 兔
- 反應性
- 人
- 保存建議
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美國加州圣地亞哥市,從事抗體等科研試劑的研發、生產和銷售。產品涵蓋了細胞凋亡、信號轉導、免疫、腫瘤、細胞生物、神經生物、傳染病等領域。ProSci擁有超過30000種單克隆抗體和多克隆抗體。ProSci的抗體大都經免疫親和層析純化,具有高純度、高親和力、特異性強等特點,所有的ProSci抗體都經過了嚴格的驗證測試和質量控制,已保證高質量的產品。此外,ProSci還提供標記二抗,重組蛋白,細胞和組織裂解液,細胞涂片,組織切片,多肽等產品與抗體配套使用。
- 注意
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該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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