- 中文名稱
HNRNPA1 抗體
- 英文名字
- HNRNPA1 Antibody
- 供應商
- ProSci
- 產品貨號
- PSI-58-858
- 產品報價
- ¥詢價/400ul

- 產品說明書
- 點擊查看
- 購買方式
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- 產品新聞

- 背景資料
- This gene belongs to the A/B subfamily of ubiquitouslynexpressed heterogeneous nuclear ribonucleoproteins (hnRNPs). ThenhnRNPs are RNA binding proteins and they complex with heterogeneousnnuclear RNA (hnRNA). These proteins are associated with pre-mRNAsnin the nucleus and appear to influence pre-mRNA processing andnother aspects of mRNA metabolism and transport. While all of thenhnRNPs are present in the nucleus, some seem to shuttle between thennucleus and the cytoplasm. The hnRNP proteins have distinct nucleicnacid binding properties. The protein encoded by this gene has twonrepeats of quasi-RRM domains that bind to RNAs. It is one of thenmost abundant core proteins of hnRNP complexes and it is localizednto the nucleoplasm. This protein, along with other hnRNP proteins,nis exported from the nucleus, probably bound to mRNA, and isnimmediately re-imported. Its M9 domain acts as both a nuclearnlocalization and nuclear export signal. The encoded protein isninvolved in the packaging of pre-mRNA into hnRNP particles,ntransport of poly A+ mRNA from the nucleus to the cytoplasm, andnmay modulate splice site selection. It is also thought have anprimary role in the formation of specific myometrial proteinnspecies in parturition. Multiple alternatively spliced transcriptnvariants have been found for this gene but only two transcripts arenfully described. These variants have multiple alternativentranscription initiation sites and multiple polyA sites. [providednby RefSeq].
- 應用類型
- WB
- 免疫原
- This HNRNPA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-294 amino acids from the C-terminal region of human HNRNPA1.
- 來源宿主
- 兔
- 反應性
- 人
- 保存建議
- Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- 其他
- ProSci Incorporated于1998年成立于美國加州圣地亞哥市,從事抗體等科研試劑的研發、生產和銷售。產品涵蓋了細胞凋亡、信號轉導、免疫、腫瘤、細胞生物、神經生物、傳染病等領域。ProSci擁有超過30000種單克隆抗體和多克隆抗體。ProSci的抗體大都經免疫親和層析純化,具有高純度、高親和力、特異性強等特點,所有的ProSci抗體都經過了嚴格的驗證測試和質量控制,已保證高質量的產品。此外,ProSci還提供標記二抗,重組蛋白,細胞和組織裂解液,細胞涂片,組織切片,多肽等產品與抗體配套使用。

- 注意
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