ZP3 抗體-ZP3 Antibody代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: The zona pellucida is an extracellular matrix thatnsurrounds the oocyte and early embryo. It is composed primarily ofnthree or four glycoproteins with various functions duringnfertilization and preimplantation development. The protein encodednby this gene is a structural component of the zona pellucida andnfunctions in primary binding and induction of the sperm acrosomenreaction. The nascent protein contains a N-terminal signal peptidensequence, a conserved ZP domain, a C-terminal consensus furinncleavage site, and a transmembrane domain. It is hypothesized thatnfurin cleavage results in release of the mature protein from thenplasma membrane for subsequent incorporation into the zonanpellucida matrix. However, the requirement for furin cleavage innthis process remains controversial based on mouse studies. Anvariation in the last exon of this gene has previously served asnthe basis for an additional ZP3 locus; however, sequence andnliterature review reveals that there is only one full-length ZP3nlocus in the human genome. Another locus encoding a bipartitentranscript designated POMZP3 contains a duplication of the lastnfour exons of ZP3, including the above described variation, andnmaps closely to this gene.

免疫原: This ZP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-380 amino acids from the C-terminal region of human ZP3.

保存建議: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

其他: ProSci Incorporated于1998年成立于美國加州圣地亞哥市,從事抗體等科研試劑的研發、生產和銷售。產品涵蓋了細胞凋亡、信號轉導、免疫、腫瘤、細胞生物、神經生物、傳染病等領域。ProSci擁有超過30000種單克隆抗體和多克隆抗體。ProSci的抗體大都經免疫親和層析純化,具有高純度、高親和力、特異性強等特點,所有的ProSci抗體都經過了嚴格的驗證測試和質量控制,已保證高質量的產品。此外,ProSci還提供標記二抗,重組蛋白,細胞和組織裂解液,細胞涂片,組織切片,多肽等產品與抗體配套使用。