TPSAB1 抗體-TPSAB1 Antibody代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: Tryptases comprise a family of trypsin-like serinenproteases, the peptidase family S1. Tryptases are enzymaticallynactive only as heparin-stabilized tetramers, and they are resistantnto all known endogenous proteinase inhibitors. Several tryptasengenes are clustered on chromosome 16p13.3. These genes arencharacterized by several distinct features. They have a highlynconserved 3' UTR and contain tandem repeat sequences at the 5'nflank and 3' UTR which are thought to play a role in regulation ofnthe mRNA stability. These genes have an intron immediately upstreamnof the initiator Met codon, which separates the site ofntranscription initiation from protein coding sequence. This featurenis characteristic of tryptases but is unusual in other genes. Thenalleles of this gene exhibit an unusual amount of sequencenvariation, such that the alleles were once thought to represent twonseparate genes, alpha and beta 1. Beta tryptases appear to be thenmain isoenzymes expressed in mast cells; whereas in basophils,nalpha tryptases predominate. Tryptases have been implicated asnmediators in the pathogenesis of asthma and other allergic andninflammatory disorders.

免疫原: This TPSAB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-87 amino acids from the Central region of human TPSAB1.

保存建議: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

其他: ProSci Incorporated于1998年成立于美國加州圣地亞哥市,從事抗體等科研試劑的研發、生產和銷售。產品涵蓋了細胞凋亡、信號轉導、免疫、腫瘤、細胞生物、神經生物、傳染病等領域。ProSci擁有超過30000種單克隆抗體和多克隆抗體。ProSci的抗體大都經免疫親和層析純化,具有高純度、高親和力、特異性強等特點,所有的ProSci抗體都經過了嚴格的驗證測試和質量控制,已保證高質量的產品。此外,ProSci還提供標記二抗,重組蛋白,細胞和組織裂解液,細胞涂片,組織切片,多肽等產品與抗體配套使用。