- 中文名稱
【干冰】Beclin-1 重組蛋白
- 英文名字
- 【干冰】Beclin-1 Recombinant Protein
- 供應商
- ProSci
- 產品貨號
- PSI-90-320
- 產品報價
- ￥詢價/10ug
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- Beclin-1 (Bcl-2 interacting coiled-coil protein; ATG6) is a multifunctional protein, well-known as a key regulator of autophagy and required for the initiation step in autophagosome formation. It interacts with several cofactors (Atg14L, UVRAG, Bif-1, rubicon, Ambra1, HMGB1, nPIST, VMP1, SLAM, IP3R, PINK and survivin) to regulate the lipid kinase PI3K protein and promote formation of PIK3C3/VPS34-containing complexes. These interactions induce autophagy, which is a process of programmed cell survival increased during periods of cell stress and extinguished during the cell cycle. Furthermore, beclin-1 is implicated in numerous biological processes, including adaptation to stress, development, endocytosis, cytokinesis, immunity, infection, tumorigenesis, aging and cell death. Beclin-1 is tightly regulated by diverse mechanisms, such as epigenetic silencing, microRNA regulation, post-translational modifications and protein-protein interactions. Multiple diseases are associated with deficiency or malfunction of beclin-1, including cancer and neurodegeneration.
- 序列
- Recombinant human beclin-1 (aa 1-450) is fused through a thrombin linker to 6 x His-tag.
- 來源宿主
- 大腸桿菌
- 溶解建議
- 艾美捷溫馨提示:開蓋前,請先離心。廠家建議您，按照該貨號產品的說明書中要求的方式進行溶解和使用。
- 保存建議
- Stable for at least 1 year after receipt when stored at -20˚C.
- 其他
- ProSci Incorporated于1998年成立于美國加州圣地亞哥市,從事抗體等科研試劑的研發、生產和銷售。產品涵蓋了細胞凋亡、信號轉導、免疫、腫瘤、細胞生物、神經生物、傳染病等領域。ProSci擁有超過30000種單克隆抗體和多克隆抗體。ProSci的抗體大都經免疫親和層析純化,具有高純度、高親和力、特異性強等特點,所有的ProSci抗體都經過了嚴格的驗證測試和質量控制,已保證高質量的產品。此外,ProSci還提供標記二抗,重組蛋白,細胞和組織裂解液,細胞涂片,組織切片,多肽等產品與抗體配套使用。
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
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