抗小鼠 CD206單克隆抗體(PE Conjugated)-Anti-Mouse CD206 Monoclonal Antibody(PE Conjugated)代理/參數/廠家-一抗-艾美捷科技有限公司

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背景資料: 該Anti-Mouse CD206 Monoclonal Antibody(PE Conjugated). CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.

其他: Reddot Biotech是由一支擁有35年醫療管理經驗團隊創辦的加拿大本土品牌，其已在ELISA產品線上深耕7個年頭，并且仍在不斷前進中。產品的質量保證也讓其越來越多被“收納進”文獻當中，產品線包括ELISA試劑盒、抗體、少量生化試劑，其中ELISA試劑盒超過6000+，物種類型較多：人；大鼠；小鼠；犬科類；牛科；魚；雞；豬；兔；山羊；綿羊；猿；馬；豚鼠等，像激素類指標促卵泡素（FSH）、促黃體激素（LH），新冠相關病毒受體ACE2、ACE以及腫瘤免疫相關的指標精氨酸酶（ARG）等已是熱門應用指標。