SKP2多克隆抗體-SKP2 Polyclonal Antibody代理/參數/廠家-內參抗體-艾美捷科技有限公司

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背景資料: 該SKP2 Polyclonal Antibody. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms.

其他: Reddot Biotech是由一支擁有35年醫療管理經驗團隊創辦的加拿大本土品牌，其已在ELISA產品線上深耕7個年頭，并且仍在不斷前進中。產品的質量保證也讓其越來越多被“收納進”文獻當中，產品線包括ELISA試劑盒、抗體、少量生化試劑，其中ELISA試劑盒超過6000+，物種類型較多：人；大鼠；小鼠；犬科類；牛科；魚；雞；豬；兔；山羊；綿羊；猿；馬；豚鼠等，像激素類指標促卵泡素（FSH）、促黃體激素（LH），新冠相關病毒受體ACE2、ACE以及腫瘤免疫相關的指標精氨酸酶（ARG）等已是熱門應用指標。