- 中文名稱
LAMC1多克隆抗體
- 英文名字
- LAMC1 Polyclonal Antibody
- 供應商
- Reddot Biotech
- 產品貨號
- RD266655A
- 產品報價
- ￥詢價/60uL ￥詢價/120uL ￥詢價/200uL
- 產品說明書
- 點擊查看
- 購買方式
- 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868
- 產品新聞
- 背景資料
- 該LAMC1 Polyclonal Antibody. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis.
- 應用類型
- IHC,IF
- 免疫原
- Recombinant fusion protein of human LAMC1 (NP_002284.3).
- 來源宿主
- 兔
- 反應性
- 人,小鼠,大鼠
- 保存建議
- 儲存于-20 ℃。 避免凍融循環。
- 其他
- Reddot Biotech是由一支擁有35年醫療管理經驗團隊創辦的加拿大本土品牌，其已在ELISA產品線上深耕7個年頭，并且仍在不斷前進中。產品的質量保證也讓其越來越多被“收納進”文獻當中，產品線包括ELISA試劑盒、抗體、少量生化試劑，其中ELISA試劑盒超過6000+，物種類型較多：人；大鼠；小鼠；犬科類；牛科；魚；雞；豬；兔；山羊；綿羊；猿；馬；豚鼠等，像激素類指標促卵泡素（FSH）、促黃體激素（LH），新冠相關病毒受體ACE2、ACE以及腫瘤免疫相關的指標精氨酸酶（ARG）等已是熱門應用指標。
- 注意
-
該頁面的中文產品信息的翻譯，僅供參考。準確的產品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。
-
