Phospho-MAP2K1（S217）/MAP2K2（S221）多克隆抗體-Phospho-MAP2K1（S217）/MAP2K2（S221） Polyclonal Antibody代理/參數/廠家-內參抗體-艾美捷科技有限公司

PRODUCT CENTER

內參抗體

產品中心

當前位置：首頁 > 產品中心 > 免疫學產品 > 內參抗體

中文名稱: Phospho-MAP2K1（S217）/MAP2K2（S221）多克隆抗體

英文名字: Phospho-MAP2K1（S217）/MAP2K2（S221） Polyclonal Antibody

供應商: Reddot Biotech

產品貨號: RD268110A

產品報價: ￥詢價/60uL ￥詢價/120uL ￥詢價/200uL

產品說明書: 點擊查看

購買方式: 銀行轉賬、電匯、支票、現金，在線支付寶及網銀支付，或直接與我們電話聯系400-6800-868

產品新聞

背景資料: 該Phospho-MAP2K1（S217）/MAP2K2（S221） Polyclonal Antibody. The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development./The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

應用類型: WB

免疫原: A phospho specific peptide corresponding to residues surrounding serine 217/221 of human MAP2K1/MAP2K2.

來源宿主: 兔

反應性: 人,小鼠,大鼠

保存建議: 儲存于-20 ℃。避免凍融循環。

其他: Reddot Biotech是由一支擁有35年醫療管理經驗團隊創辦的加拿大本土品牌，其已在ELISA產品線上深耕7個年頭，并且仍在不斷前進中。產品的質量保證也讓其越來越多被“收納進”文獻當中，產品線包括ELISA試劑盒、抗體、少量生化試劑，其中ELISA試劑盒超過6000+，物種類型較多：人；大鼠；小鼠；犬科類；牛科；魚；雞；豬；兔；山羊；綿羊；猿；馬；豚鼠等，像激素類指標促卵泡素（FSH）、促黃體激素（LH），新冠相關病毒受體ACE2、ACE以及腫瘤免疫相關的指標精氨酸酶（ARG）等已是熱門應用指標。