P62/SQSTM1多克隆抗體-P62/SQSTM1 Polyclonal Antibody代理/參數/廠家-內參抗體-艾美捷科技有限公司

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背景資料: 該P62/SQSTM1 Polyclonal Antibody. Sequestosome 1 (SQSTM1/p62) is a multifunctional adaptor protein implicated in selective autophagy,cell signaling pathways,and tumorigenesis. p62 has been implicated in shuttling ubiquitinated and sometimes aggregated proteins for autophagic degradation. As a autophagy-specific substrate,p62 is degraded during the autophagic process,which makes intracellular level of p62 as a marker for autophagy flux. p62 is at the cross-roads of several signaling pathways including Ras/ Raf/ MAPK and NFκB and plays important role in cancer. p62 is a component of inclusion bodies/ protein aggregates found in human diseases,including Huntington's disease,Alzheimer's disease,Parkinson's disease in the brain,and nephropathic cystinosis in kidney (22074114,22860231,22714671). The molecular weight of p62 is predicted as 48/ 38 kDa,while western blot analyses using this antibody demonstrate the major band around 60-62 kDa in various tissues.

其他: Reddot Biotech是由一支擁有35年醫療管理經驗團隊創辦的加拿大本土品牌，其已在ELISA產品線上深耕7個年頭，并且仍在不斷前進中。產品的質量保證也讓其越來越多被“收納進”文獻當中，產品線包括ELISA試劑盒、抗體、少量生化試劑，其中ELISA試劑盒超過6000+，物種類型較多：人；大鼠；小鼠；犬科類；牛科；魚；雞；豬；兔；山羊；綿羊；猿；馬；豚鼠等，像激素類指標促卵泡素（FSH）、促黃體激素（LH），新冠相關病毒受體ACE2、ACE以及腫瘤免疫相關的指標精氨酸酶（ARG）等已是熱門應用指標。