JNK1/2/3多克隆抗體-JNK1/2/3 Polyclonal Antibody代理/參數/廠家-內參抗體-艾美捷科技有限公司

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背景資料: 該JNK1/2/3 Polyclonal Antibody. c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1α1,JNK1β1, JNK2α1, JNK2β1 and JNK3α1, which represent the p46 isoforms, and JNK1α2, JNK1β2, JNK2α2, JNK2β2 and JNK3β2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and ransformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38.

免疫原: Synthesized peptide derived from human JNK1/2/3 around the non-phosphorylation site of Thr183.

其他: Reddot Biotech是由一支擁有35年醫療管理經驗團隊創辦的加拿大本土品牌，其已在ELISA產品線上深耕7個年頭，并且仍在不斷前進中。產品的質量保證也讓其越來越多被“收納進”文獻當中，產品線包括ELISA試劑盒、抗體、少量生化試劑，其中ELISA試劑盒超過6000+，物種類型較多：人；大鼠；小鼠；犬科類；牛科；魚；雞；豬；兔；山羊；綿羊；猿；馬；豚鼠等，像激素類指標促卵泡素（FSH）、促黃體激素（LH），新冠相關病毒受體ACE2、ACE以及腫瘤免疫相關的指標精氨酸酶（ARG）等已是熱門應用指標。