Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.
產品描述
該CC2D1A ELISA Kit (Human)的產品描述請參考該產品的說明書
產品特點
ELISA試劑盒
保存建議
2°C to 8°C|-20°C
其他
Aviva Systems Biology總部位于加利福尼亞州圣迭戈，在中國北京設有辦公室，專注于為研究需求提供多克隆和單克隆抗體、ELISA試劑盒、蛋白質和定制服務。Aviva Systems Biology生產了24,000種經過驗證的多克隆抗體，并提供近20,000種ELISA試劑盒，定制實驗室服務包括蛋白表達和純化、抗體開發，以及ELISA的開發、驗證和生產。Aviva Systems Biology為與獨特物種和靶標相關的研究提供獨特工具，研究領域包括轉錄因子、癌癥、心血管、細胞生物學、DNA損傷和修復、表觀遺傳學、信號轉導、細胞分化、干細胞生物學等等。
