This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade (PubMed:7525274). Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage (PubMed:28657829).
產品描述
該CD55 ELISA Kit (Human)的產品描述請參考該產品的說明書
產品特點
ELISA試劑盒
保存建議
2°C to 8°C|-20°C
其他
Aviva Systems Biology總部位于加利福尼亞州圣迭戈,在中國北京設有辦公室,專注于為研究需求提供多克隆和單克隆抗體、ELISA試劑盒、蛋白質和定制服務。Aviva Systems Biology生產了24,000種經過驗證的多克隆抗體,并提供近20,000種ELISA試劑盒,定制實驗室服務包括蛋白表達和純化、抗體開發,以及ELISA的開發、驗證和生產。Aviva Systems Biology為與獨特物種和靶標相關的研究提供獨特工具,研究領域包括轉錄因子、癌癥、心血管、細胞生物學、DNA損傷和修復、表觀遺傳學、信號轉導、細胞分化、干細胞生物學等等。