Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
序列
該Recombinant human Cell surface glyco protein MUC18的序列請參考該產品的說明書
來源宿主
該Recombinant human Cell surface glyco protein MUC18的來源宿主請參考該產品的說明書
溶解建議
該Recombinant human Cell surface glyco protein MUC18的溶解建議請參考該產品的說明書
保存建議
該Recombinant human Cell surface glyco protein MUC18的保存建議請參考該產品的說明書
其他
Aviva Systems Biology總部位于加利福尼亞州圣迭戈,在中國北京設有辦公室,專注于為研究需求提供多克隆和單克隆抗體、ELISA試劑盒、蛋白質和定制服務。Aviva Systems Biology生產了24,000種經過驗證的多克隆抗體,并提供近20,000種ELISA試劑盒,定制實驗室服務包括蛋白表達和純化、抗體開發,以及ELISA的開發、驗證和生產。Aviva Systems Biology為與獨特物種和靶標相關的研究提供獨特工具,研究領域包括轉錄因子、癌癥、心血管、細胞生物學、DNA損傷和修復、表觀遺傳學、信號轉導、細胞分化、干細胞生物學等等。