人IFN-γ在大腸桿菌中表達(dá)的人干擾素γ重組蛋白。

1、II型干擾素

2、非糖基化多肽二聚體

PBL Assay Science/艾美捷人IFN-γ（PBL-11500-1）規(guī)格：

配方 在含有 0.1% 牛血清白蛋白 （BSA） 的磷酸鹽緩沖鹽水 （PBS） 中冷凍提供

分子量 16.8 千達(dá)

源 從大腸桿菌中表達(dá)的人 T 淋巴細(xì)胞中獲得的人 cDNA

純度 > 95% 通過(guò)考馬斯藍(lán)

內(nèi)毒素水平 < 1 EU/μg 染色的 SDS-PAGE

生物 活性 使用細(xì)胞病變抑制測(cè)定法對(duì)伴有腦心肌炎病毒 （EMCV） 的人肺癌細(xì)胞系 A549 進(jìn)行測(cè)量

存儲(chǔ) 用于將完整活動(dòng)存儲(chǔ)保留在 -70oC或以下，避免反復(fù)凍融循環(huán)

PBL Assay Science人IFN-γ引用文獻(xiàn)：

Crawford, J.D., et al., (2023), "The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE", JCI Insight., e169344, PMID: 37733447, DOI: 10.1172/jci.insight.169344

Fung, S. K., et al.,(2022), "SARS-CoV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1", Cell & Bioscience, 12:36, DOI: 10.1186/s13578-022-00770-1, PMID: 35317858,

Abt, E.R., et al., (2022), "Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells", Cell Reports, 38:110236, DOI: 10.1016/j.celrep.2021.110236

Le-Trilling, Vu Thuy Khanh, et al. (2020). The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity. Cell Reports, 19 pgs. PMID: 32075763. 

Raviram, Ramya, et al. (2018). Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate. Genome Biology, 19 pgs. PMID: 30541598.

Kativhu, Chido, et al. (2016). A Model to Explain How the Bacille Calmette Guerin (BCG) Vaccine Drives Interleukin-12 Production in Neonates. PLOS One, 12 pgs. PMID: 27571272.

Neufeldt, Christopher, et al. (2013). Hepatitis C Virus-Induced Cytoplasmic Organelles Use the Nuclear Transport Machinery to Establish an Environment Conducive to Virus Replication. PLOS Pathogens, 15 pgs. PMID: 24204278.

PBL Assay Science（又名：Pestka Biomedical Laboratories, Inc.）作為干擾素和細(xì)胞因子蛋白和抗體以及預(yù)包裝的免疫測(cè)定試劑盒的高質(zhì)量制造商而享有盛譽(yù)。生產(chǎn)和銷(xiāo)售的高品質(zhì)干擾素產(chǎn)品和生物標(biāo)志物檢測(cè)試劑盒在很多高影響力出版物中都有引用，并已在具有挑戰(zhàn)性的樣本中進(jìn)行了外部驗(yàn)證。PBL Assay Science提供各種干擾素亞型的蛋白，抗體和檢測(cè)試劑盒，如：IFN-Alpha（IFN-ɑ 2a，IFN-ɑ 2b，IFN-ɑ 5，IFN-ɑ 6，IFN-ɑ 7，IFN-ɑ 14，IFN-ɑ 16，IFN-ɑ 17......），IFN-Beta（IFN-β 1a，IFN-β 1b），IFN-Lambda（IFN-λ），IFN-Omega（IFN-ω），IFN-Gamma（IFN-γ）......艾美捷科技是PBL Assay Science的中國(guó)代理商，為科研工作者提供優(yōu)質(zhì)的產(chǎn)品與服務(wù)。