鬼筆環(huán)肽（Phalloidin）是從毒蕈類鬼筆鵝膏中得到的有毒環(huán)狀七肽，能選擇性的與動(dòng)植物體內(nèi)的肌動(dòng)蛋白結(jié)合，且只跟聚合的微絲結(jié)合，而不跟單體的肌動(dòng)蛋白結(jié)合，使鬼筆環(huán)肽熒光偶聯(lián)物成為研究細(xì)胞內(nèi)肌動(dòng)蛋白微絲的神器。

作為專業(yè)的生命科學(xué)醫(yī)藥原料供應(yīng)商，CytoSkeleton中國區(qū)金牌代理，艾美捷科技為您推薦眾多文章引用的：《羅丹明標(biāo)記鬼筆環(huán)肽（Rhodamine Phalloidin）》

Fig. 3T3成纖維細(xì)胞

* 本產(chǎn)品僅適用于科研用途.

實(shí)驗(yàn)步驟：具體羅丹明鬼筆環(huán)肽（Rhodamine Phalloidin）使用，請參閱說明書。

FAQ：

1.這個(gè)產(chǎn)品是否可以用于活細(xì)胞的F-actin染色呢？

很遺憾，PHDR1僅適用于固定后的細(xì)胞；如果需要染活細(xì)胞F-actin，推薦您使用活細(xì)胞F-actin微絲蛋白染色試劑盒。

2.除了橘紅色羅丹明標(biāo)記的鬼筆環(huán)肽，還有其它顏色的偶聯(lián)可選嗎？

當(dāng)然，您還可以選擇下方其它的產(chǎn)品：

發(fā)表文章：

1.Danielsson, B. E. et al. Lamin microaggregates lead to altered mechanotransmission in progerin-expressing cells. Nucleus 11, 194–204 (2020).

2.Yang, S. et al. Self-assembling peptide hydrogels functionalized with LN- And BDNF- mimicking epitopes synergistically enhance peripheral nerve regeneration. Theranostics 10, 8227–8249 (2020).

3.Zhu, J. et al. Bioactive poly (methyl methacrylate) bone cement for the treatment of osteoporotic vertebral compression fractures. Theranostics 10, 6544–6560 (2020).

4.Lu, F., Sun, X., Xu, X. & Jiang, X. SILAC-based proteomic profiling of the suppression of TGF-β1-induced lung fibroblast-to-myofibroblast differentiation by trehalose. Toxicol. Appl. Pharmacol. 391, 114916 (2020).

5.Huang, Yuxing et al. “Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance.” Cells vol. 8,10 1264. 16 Oct. 2019, doi:10.3390/cells8101264

6.Shan, Lijun et al. “In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration.” Materials (Basel, Switzerland) vol. 12,5 815. 10 Mar. 2019, doi:10.3390/ma12050815

7.Liang, Fengyi et al. “Juxtanodin in retinal pigment epithelial cells: Expression and biological activities in regulating cell morphology and actin cytoskeleton organization.” The Journal of comparative neurology vol. 526,2 (2018): 205-215. doi:10.1002/cne.24301

8.Zhang, Ying et al. “Effects of testosterone on the expression levels of AMH, VEGF and HIF-1α in mouse granulosa cells.” Experimental and therapeutic medicine vol. 12,2 (2016): 883-888. doi:10.3892/etm.2016.3436

9.Lee et al., 2013. Phellinus baumii extract influences pathogenesis of Brucella abortus in phagocyte by disrupting the phagocytic and intracellular trafficking pathway. J. Appl. Microbiol. 114, 329–338.

10.Baruzzi and Berton, 2012. The tyrosine kinase Abl is a component of macrophage podosomes and is required for podosome formation and function. E. J. Immunol. doi: 10.1002/eji.201142270.

11.Shiozaki et al., 2012. XB130 as an Independent Prognostic Factor in Human Esophageal Squamous Cell Carcinoma. Ann. Surg. Oncology. doi: 10.1245/s10434-012-2474-4.

12.Gallo et al., 2012. Regulation of the Actin Cytoskeleton by Rho Kinase Controls Antigen Presentation by CD1d. J. Immunol. doi: 10.4049/jimmunol.1101484.

13.Lee et al., 2012. Dysadherin expression promotes the motility and survival of human breast cancer cells by AKT activation. Cancer Sci. v 103, pp 1280-1289.

14.Shi et al., 2012. MTA-enriched nanocomposite TiO2-polymeric powder coatings support human mesenchymal cell attachment and growth. Biomed. Mater. 7:055006. doi:10.1088/1748-6041/7/5/055006.

15.Ezratty et al., 2005. Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase. Nat. Cell Biol. v 7, pp 581-590.

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