Cytoskeleton小G蛋白&GEF產(chǎn)品線暖春特惠啦~

發(fā)布者：艾美捷科技發(fā)布時間：2023-03-10

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小G蛋白&GEF產(chǎn)品線

為答謝和回饋廣大科研工作者們長期以來對武漢艾美捷科技有限公司的大力支持，艾美捷科技聯(lián)合細胞骨架領(lǐng)域頂級供應(yīng)商Cytoskeleton聯(lián)合推出：小G蛋白&GEF產(chǎn)品線超值大促，一年僅此一次，千萬不要錯過啊！本次促銷活動產(chǎn)品涵蓋 GEFs, 小G蛋白和 G-LISA活化試劑盒等。

小G蛋白(Small G Protein)因分子量只有20—30KD 而得名，同時具有GTP酶活性，在細胞信號通路中發(fā)揮分子開關(guān)的功能，參與調(diào)控很多生物學(xué)過程，包括分泌活動和細胞骨架的裝配等。目前發(fā)現(xiàn)的小G蛋白包括Rho, Rac, Arf1 & 6, Ras, Ral等。小G蛋白的共同特點是，當(dāng)結(jié)合了GTP時即成為活化形式，這時可作用于下游分子使之活化，而當(dāng)GTP水解成為GDP時（自身為GTP酶）則恢復(fù)到非活化狀態(tài)。

小G蛋白&GEF產(chǎn)品線

Pull-down和G-LISA實驗都被廣泛地用于研究小G蛋白的活性。Pull-down實驗又叫蛋白質(zhì)體外結(jié)合實驗，可用于測定活性的GTPase亞型，可作為對G-LISA實驗的補充。G-LISA實驗是一種改進的ELISA，可測定3D細胞系、原代細胞裂解液及組織裂解液中有活性的GTPase，使GTPase定量的準確性增加。

活動詳情：

時間：2023年3月15日-2023年4月30日

對象：僅限中國區(qū)終端客戶

品目：GEFs, 小G蛋白和G-LISA活化試劑盒等產(chǎn)品（詳情見下方活動品目列表）

內(nèi)容： 直享 6.5 折超低優(yōu)惠！

活動品目列表：

分類	貨號	產(chǎn)品名稱	規(guī)格	原價	折后價
抗體	CSK-ACD03	Anti-Cdc42 Mouse Monoclonal Antibody	2x200ul	5919	3847
	CSK-ARC03	Anti-Rac1 specific mouse MAb	2x100ul	5919	3847
	CSK-ARC03-S	Anti-Rac1 specific mouse MAb(sample size)	1x25ul	1665	1082
試劑盒	CSK-BK008	Ras Activation Assay Biochem Kit	KIT50assays	11991	7794
	CSK-BK008-S	Ras Activation Assay Biochem Kit	KIT20assays	6073	3947
	CSK-BK030	Combo RhoA/Rac1/Cdc42 Activation Assay Kit	KIT3x10assays	15798	10269
	CSK-BK032-S	Arf1 Pulldown Activation Assay Kit	KIT20assays	7290	4739
	CSK-BK033-S	Arf6 Pulldown Activation Assay Kit	KIT20assays	7290	4739
	CSK-BK034	Cdc42 Pulldown Activation Assay Kit	KIT50assays	11991	7794
	CSK-BK034-S	Cdc42 Pulldown Activation Assay Kit	KIT20assays	6073	3947
	CSK-BK035	Rac1 Pulldown Activation Assay Kit	KIT50assays	11991	7794
	CSK-BK035-S	Rac1 Pulldown Activation Assay Kit	KIT20assays	6073	3947
	CSK-BK036	RhoA Pulldown Activation Assay Kit	KIT80assays	11991	7794
	CSK-BK036-S	RhoA Pulldown Activation Assay Kit	KIT20assays	6073	3947
	CSK-BK040	RalA Activation Assay Biochem Kit	KIT50assays	11991	7794
	CSK-BK100	GEF Exchange Assay	KIT60-300assays	11113	7223
	CSK-BK105	GAP Assay Kit	KIT80-160assays	11066	7193
	CSK-BK121	RhoA G-LISA Activation Assay (luminescence)	KIT96assays	14920	9698
	CSK-BK124	RhoA G-LISA Activation Assay (absorbance)	KIT96assays	14920	9698
	CSK-BK124-S	RhoA G-LISA Activation Assay (absorbance)	KIT24assays	9001	5851
	CSK-BK124-XL	RhoA G-LISA Activation Assay (absorbance)	大規(guī)格	詢價	詢價
	CSK-BK125	Rac1,2,3 G-LISA Activation Assay Kit	KIT96assays	14920	9698
	CSK-BK126	Rac1 G-LISA Activation Assay Kit	KIT96assays	14920	9698
	CSK-BK127	Cdc42 G-LISA Activation Assay Kit	KIT96assays	14920	9698
	CSK-BK127-S	Cdc42 G-LISA Activation Assay Kit	KIT24assays	9001	5851
	CSK-BK128	Rac1 G-LISA Activation Assay Kit	KIT96assays	14920	9698
	CSK-BK128-S	Rac1 G-LISA Activation Assay Kit	KIT24assays	9001	5851
	CSK-BK129	RalA G-LISA Activation Assay Kit	KIT96assays	14920	9698
	CSK-BK131	Ras G-LISA Activation Assay Kit	KIT96assays	14920	9698
	CSK-BK131-XL	Ras G-LISA Activation Assay Kit	大規(guī)格	詢價	詢價
	CSK-BK135	G-LISA Bundle (BK135 = BK124-S + BK127-S + BK128-S)	3KITS(24assays/kit)	24861	16160
	CSK-BK150	RhoA ELISA Kit	KIT96assays	8138	5290
蛋白	CSK-C17G01-A	Cdc42-GST protein: dominant negative	1x25ug	6751	4388
	CSK-C6101-A	Cdc42-His Protein: constituitively active	1x10ug	6751	4388
	CSK-CD01-A	Cdc42-His Protein: Wild type	1x100ug	6751	4388
	CSK-CD01-C	Cdc42-His Protein: Wild type	3x100ug	11914	7744
	CSK-CD01-XL	Cdc42-His Protein: Wild type	1x1mg	23813	15478
	CSK-CDG01-C	Cdc42-GST Protein: Wild type	8x25ug	9926	6452
	CSK-CS-GE03	Ras-GRF GEF protein (human recomb. CDC25 domain, MBP tagged)	1x100ug	5949	3867
	CSK-CS-GE04	Tiam1 GEF protein (human recomb. DHPH domain, MBP tagged)	1x100ug	5949	3867
	CSK-CS-GE05	Vav1 GEF protein (human recomb. DHPHC1 domain Y174D mutant, 6xHis tagged)	1x100ug	5949	3867
	CSK-CS-GE06	Vav2 GEF protein (human recomb. DH domain, 6xHis tagged)	1x100ug	5949	3867
	CSK-CS-GE07	ARNO Protein: GEF (Sec7) domain (aa31- 267, human recomb., 6xHis tagged)	1x100ug	5949	3867
	CSK-CS-GE08	SOS2 exchange domain (563-1051) protein (Human recombinant)	1x100ug	5949	3867
	CSK-CS-GE09	RAPGEF5 Protein: Ras association and exchange domain (57– 580) wild type. (Human recombinant, GST tagged)	1x100ug	5949	3867
	CSK-CS-RS02	N-Ras Protein; wild-type (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS03	K-Ras4B Protein: wild-type (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS04	K-Ras4B Mutant Protein: G12V (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS05	R-Ras Protein: wild-type (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS06	K-Ras4B Mutant Protein: G13D (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS07	K-Ras4B Mutant Protein: G13S (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS08	K-Ras4B Mutant Protein: K128A (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS09	K-Ras4B Mutant Protein: Q61P (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS10	K-Ras4B Mutant Protein: R135A (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS11	K-Ras4B Mutant Protein: G12D+I36N (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS12	K-Ras4B Mutant Protein: G12D+D38A (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CS-RS13	K-Ras4B Mutant Protein: G12D (human recombinant with 6xHis-tag)	1x100ug	6751	4388
	CSK-CT03-A	C3 transferase protein	1x25ug	3406	2214
	CSK-CT03-C	C3 transferase protein	4x25ug	11930	7754
	CSK-GAP01-A	Rho GAP Protein GST	1x50ug	4716	3066
	CSK-GAP01-B	Rho GAP Protein GST	4x50ug	11575	7524
	CSK-GAS01-A	Rho GAP Protein: catalytic domain GST	1x50ug	4716	3066
	CSK-GAS01-B	Rho GAP Protein: catalytic domain GST	4x50ug	11575	7524
	CSK-GDI01-A	GDP dissociation inhibitor protein GST fusion	1x25ug	4716	3066
	CSK-GE01-A	Dbs protein GEF domain - HIS fusion	2x50ug	4763	3096
	CSK-GE02	SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged)	1x100ug	5641	3667
	CSK-GE02-XL	SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged)	1x1mg	28344	18424
	CSK-PAK01-A	PAK Rac1/Cdc42 binding domain protein	1x250ug	6427	4178
	CSK-PAK01-B	PAK Rac1/Cdc42 binding domain protein	4x250ug	17047	11080
	CSK-PAK02-A	PAK Beads, Rac1/Cdc42 binding domain protein on beads	1x500ug	7460	4849
	CSK-PAK02-B	PAK Beads, Rac1/Cdc42 binding domain protein on beads	4x500ug	22796	14817
	CSK-R17G01-A	Rac1 GST Protein: dominant negative	1x25ug	6751	4388
	CSK-R6101-A	Rac1 His Protein: constitutively active	1x10ug	6751	4388
	CSK-R6301-A	RhoA His Protein: constitutively active	1x10ug	6751	4388
	CSK-RC01-A	Rac1 His Protein: wild type	1x100ug	6751	4388
	CSK-RC01-C	Rac1 His Protein: wild type	3x100ug	11914	7744
	CSK-RC01-XL	Rac1 His Protein: wild type	1x1mg	23813	15478
	CSK-RC02-A	Rac2 His Protein: wild type	1x100ug	6751	4388
	CSK-RCG01-C	Rac1 GST Protein: wild type	8x25ug	9926	6452
	CSK-RF02-A	Raf protein ras binding domain on GST beads	1x2mg	7938	5159
	CSK-RF02-B	Raf protein ras binding domain on GST beads	4x2mg	23027	14967
	CSK-RH01-A	RhoA His Protein: wild type	1x100ug	6751	4388
	CSK-RH01-C	RhoA His Protein: wild type	3x100ug	11914	7744
	CSK-RH01-XL	RhoA His Protein: wild type	1x1mg	23813	15478
	CSK-RH03-A	RhoC His Protein: wild type	1x100ug	6751	4388
	CSK-RHG01-C	RhoA GST Protein: wild type	8x25ug	9926	6452
	CSK-RR02-A	Rap1b protein (Human wild type, His)	1x100ug	6751	4388
	CSK-RS01-A	H-Ras Protein; wild type 6xHis Tag	1x100ug	6751	4388
	CSK-RS01-C	H-Ras Protein; wild type 6xHis Tag	3x100ug	11914	7744
	CSK-VCG03-A	VCA domain of WASP (GST fusion)	1x500ug	8169	5310
	CSK-RT01-A	Rhotekin RBD protein GST fusion	1x500ug	7521	4889
微珠	CSK-RT02-A	Rhotekin RBD protein on GST beads	2x2mg	9926	6452
	CSK-RT02-B	Rhotekin RBD protein on GST beads	6x2mg	23736	15428
	CSK-GGA07-A	GGA3-PBD Arf Affinity Beads	1x500ug	8739	5680
抑制劑&激活劑	CSK-CN01-A	Rho Activator	5x10units	3406	2214
	CSK-CN01-B	Rho Activator	20x10units	12423	8075
	CSK-CN02-A	Rac and Cdc42 Activator	5x10units	3406	2214
	CSK-CN02-B	Rac and Cdc42 Activator	20x10units	12423	8075
	CSK-CN03-A	Rho activator II	3x20ug	3406	2214
	CSK-CN03-B	Rho activator II	9x20ug	9602	6241
	CSK-CN03-XL	Rho activator II	大規(guī)格	詢價	詢價
	CSK-CN04-A	Rho/Rac/Cdc42 Activator I	3x20ug	3406	2214
	CSK-CN04-B	Rho/Rac/Cdc42 Activator I	9x20ug	9602	6241
	CSK-CT04-A	Cell Permeable Rho Inhibitor (C3 Trans based))	1x20ug	3406	2214
	CSK-CT04-B	Cell Permeable Rho Inhibitor (C3 Trans based))	5x20ug	10234	6652
	CSK-CT04-C	Cell Permeable Rho Inhibitor (C3 Trans based))	20x20ug	26911	17492
	CSK-CT04-XL	Cell Permeable Rho Inhibitor (C3 Trans based))	大規(guī)格	詢價	詢價

* 本活動最終解釋權(quán)歸艾美捷科技所有

Cytoskeleton公司成立于1993年，專注于生物化學(xué)和細胞過程研究中的純化蛋白和便捷試劑盒開發(fā)與生產(chǎn)。公司提供藥物篩選、信號轉(zhuǎn)導(dǎo)、蛋白質(zhì)轉(zhuǎn)錄后修飾（PTM）、細胞骨架研究相關(guān)的系列試劑盒和產(chǎn)品，尤其以細胞骨架相關(guān)研究見長，既能滿足于樣品較少的科學(xué)研究，也可以用于小規(guī)模篩選研究和高通量大規(guī)模篩選研究。