Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a neurotrophic factor that is closely related to other neurotrophic factors, such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes RET and GFRα1-4, to promote dopamine uptake, survival and differentiation of neurons. Recombinant rat GDNF is a non-glycosylated homodimer, containing two 135 amino acid chains, with a total molecular weight of 30.1 kDa.
序列
該Rat Glial Derived Neurotrophic Factor Recombinant Protein - 012-001-V10-0010的詳細(xì)信息查看Rockland提供的產(chǎn)品說明書。
來源宿主
Other - E.coli
溶解建議
Restore with deionized water (or equivalent)
保存建議
Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.