COX-2, also known as prostaglandin H synthase, was identified less than a decade ago.? Its discovery was followed by a period of discovery and drug development to create a “super aspirin” and led to insights into arthritis, Alzheimer's disease, colorectal cancer and regulation of brain and kidney function in search of better treatments for degenerative and inflammatory diseases.??Cox-2 is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression.? Given its role in synthesizing prostaglandins, Cox-2 is therefore of interest in studying immune response regulation.
應用類型
ELISA,Immunohistochemistry,Western Blot,
免疫原
This whole rabbit serum was prepared by repeated immunizations with a fusion protein corresponding to the carboxy-terminus of human Cox-2.
來源宿主
Rabbit
反應性
H. sapiens (Human); Mus musculus (Mouse); Rattus (Rat)
保存建議
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.