Wdr5 belongs to the family of WD repeat proteins which are involved in different cellular processes such as cell cycle progression, signal transduction, apoptosis, and gene regulation. It is a component of the Set1A and Set1B histone H3 methylation complexes. These complexes methylate lysine 4 of H3, thereby activating gene transcription. Wdr5 interacts with H3 dimethyl K4, but not with tri or mono methylated H3K4. Anti-Wdr5 Antibody is ideal for research in Cell Cycle Control, Signal Transduction, Apoptosis, Epigenetics, Gene Expression and Cancer.
應(yīng)用類型
ELISA,Western Blot,
免疫原
Anti-Wdr5 Antibody was produced in rabbits by repeated immunizations with two synthetic peptides containing an amino acid sequence from the internal part of mouse Wdr5.
來源宿主
Rabbit
反應(yīng)性
Mus musculus (Mouse)
保存建議
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.