- 中文名稱
【干冰】Anti-KDM1B (RABBIT) Antibody - 100-401-W43
- 英文名字
- 【干冰】Anti-KDM1B (RABBIT) Antibody - 100-401-W43
- 供應(yīng)商
- Rockland
- 產(chǎn)品貨號
- 100-401-W43
- 產(chǎn)品報(bào)價(jià)
- ¥詢價(jià)/100uL

- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
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- 產(chǎn)品新聞

- 背景資料
- KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Anti-KDM1B is ideal for research in Epigenetics and Gene Expression.
- 應(yīng)用類型
- ELISA,
- 免疫原
- Anti-KDM1B Antibody was produced in rabbits by repeated immunizations with two different synthetic peptides containing a sequence from the N-terminus and internal region of the human KDM1B protein.
- 來源宿主
- Rabbit
- 反應(yīng)性
- H. sapiens (Human)
- 保存建議
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 其他
- Rockland成立于1962年,是一家老牌抗體原產(chǎn)企業(yè),其位于美國費(fèi)城郊區(qū)的農(nóng)場保有近20種實(shí)驗(yàn)動(dòng)物。Rockland公司為生命科學(xué)領(lǐng)域提供豐富的、高質(zhì)量的抗體,包括載脂蛋白、細(xì)胞周期/凋亡、細(xì)胞因子、細(xì)胞信號蛋白、酶類、細(xì)胞外基質(zhì)、轉(zhuǎn)錄因子(NFkB)和泛素(Ubiquitin)等識別抗體,應(yīng)用范圍包括Western blot、免疫組化、免疫熒光和ELISA等。另外,Rockland也生產(chǎn)特別齊全的二抗,包括純化、生物素、HRP/ALP、熒光標(biāo)記二抗,應(yīng)用十分廣泛。

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